Journal of chemical and pharmaceutical research, 2014, 61. Cytoprotection of annona squamosa was apparent with protection in alcohol induced, aspirin models and enhanced mucin level in pyloric ligation model 12. Custard apple is distributed throughout india and belongs to the genus annona and family annonaceae. Since, annond squanlosa family annona ceae extracts have shown insecticidal activity against stored grain insects dixit 19921, we deemed it appropriate to study the larvicidal and chemosterilant activity of a. The seedless cuban sugar apple was introduced into florida in 1955, has produced scant crops of slightly malformed fruits with mere vestiges of undeveloped seeds. Contents of constituents and antioxidant activity of seed.
The hydro alcoholic extract of leaves of annona squamosa l. Both the extracts caused significant apoptoictumor cell death with enhance. This plant is reputed to possess several medicinal properties asolkar et al. Screening of phytochemicals and antibacterial activity of. Antiinfective and anticancer properties of the annona.
The fruit juice was used as a diuretic agent and to treat leprosy and liver. Annana squamosa extract showed potent activity against sitophilus oryzae pest. Anthelmintic activity the anthelmintic activities of the annona squamosa and its leaf extract have been studied using various models. This herb has various medicinal effects, like astringent, anthelmintic, diuretic. Reddy college of pharmacy, heesargatta, soldevanahalli, bangalore 560 090. In the ayurvedic system of medicine, herbal extract have been used from centuries, because many constituent with more than one mechanism of action are considered to be beneficial. Peptic ulcer is a disease that affects aanalgesic and antiinflammatory activity. Seeds, leaves and immature dried fruits are used as an inseticide for bedbugs, head and body iices. Diuretic and antioxidant activities of the aqueous extract of leaves of. Some of the active constituents have been identified and investigated for biological actions while the rest are yet to be explored. This paper describes the presence of some phytochemicals in annona squamosa which are responsible for antibacterial activity especially against the enteric pathogens.
Antidiabetic activity of aqueous leaf extract of annona squamosa in streptozotocinnicotinamide type 2 diabetic rats. This shows that diuretic activity of aqueous extract of v. A few studies have discussed the existence of different promising cultivars or genotypes of a. It efficiently suppressed plant diseases, caused by phytophthora infestans and puccinia recondita. The anthelmintic activities of the annona squamosa and its leaf extract have been studied using various models. Annona squamosa is a medicinal plant which has been used in alternative medicine from ancient times. An overview on medicinally important plant annona reticulata linn. It is native of tropical america and west indies, growing up to 3 to 8 meters tall.
Phytochemical and hptlc studies of various extracts of annona squamosa annonaceae. Efficacy of the extract from sugar apple leaves annona. Mona agrawal1, yogesh agrawal2, prakash itankar1, arun patil1, jayshree vyas1, amruta kelkar1 1department of pharmaceutical sciences, rashtrasant tukadoji maharaj, nagpur university, nagpur,mh,india. Annona squamosa, pharmacological activities, custard apple, sugar apple, pharmacology 1. The leaf of annona squamosa has been reported to contain essential oil, terpenes. Antibacterial and insecticidal activity of crude seed. Satyanarayana 2 1department of pharmacognosy, acharya and b. Annona squamosa linn is used as an antioxidant, antidiabetics, hepatoprotective, cytotoxicactivity, genetoxicity, antitumour activity, antilice agent. Effect of annona squamosa leaf extract on pentylenetetrazol induced convulsions. The preliminary phytochemical investigation was carried out to identify the. Antidiabetic and antihyperlipidemic activity of annona. Annona squamosa sugar apple is used traditionally as an antiinfective and antioxidant. Antibacterial and insecticidal activity of crude seed extracts of annona squamosa l.
Diuresis among last instar nymphs of periplaneta americana. The purpose of this paper is to investigate various extracts of annona squamosa l annonanceae and carica papaya l caricaceae seeds for their antioxidant activity, free radical scavenging ability, total phenolic and flavonoid contents. Contents of constituents and antioxidant activity of seed and pulp extracts of annona coriacea and annona sylvatica benites, rsr. Effect of annona squamosa leaf extract on spontaneous locomotor activity. Annona muricata is a member of the annonaceae family and is a fruit tree with a long history of traditional use. The sugar apple is one of the most important fruits in the interior of brazil and is conspicuous in the markets of bahia. The present study describes the larvicidal activity of annona squamosa plant over c. Regarding antioxidant contents and antioxidant activities, although it exhibited the inhibitory effect on the id1 expression, the extract of annona squamosa was not the richest. Request pdf pharmacological activities of annona squamosa. Annonaceae, is also known as the sugar apple or custard apple in india or sweetsop. Pdf antidiabetic activity of aqueous leaf extract of. Phytochemical and hptlc studies of various extracts of. Caryophyllene large population throughout the world and it is causedoxide which was isolated from an unsaponified petroleum mainly due to the development of gastric lesions, whenether extract from the bark of annona squamosa was there is a.
The objective of the present study is to investigate insecticidal activity of ethanolic extract of annana squamosa. Chromosomal aberration of annona squamosa the chromosomal aberration showed that the single application of annona squamosa extract at the dose of 250 and 500mgkg body wt. The plant annona squamosa traditionally known as custard apple possesses potent bioactive principles in all its parts. The present investigation was undertaken to study the effects of fruit peel extracts of annona squamosa on blood glucose and lipid profile in streptozotocin induced diabetic rats. Nematicidal and antifungal activities of annonaceous. The pharmacological properties of annona squamosa linn. The methanol extract of annona squamosa seeds was highly active against two phytoparasitic nematodes, bursaphelenchus xylophilus and meloidogyne incognita. This suggests that the suppressive effect of annona squamosa extract may not be primarily responsible by antioxidant contents and activities.
It is mainly cultivated for the commercial value of the fruits. Fatty acids analysis, antioxidant and biological activity. Ten annonaceous acetogenins aas were isolated, and their chemical structures were identified by mass and nuclear magnetic. P abstract this study was undertaken to investigate the antioxidant activity of ethanolic extract of annona squamosa. It is not described in the classical ayurvedic literature. Insecticidal activity of ethanolic extract of leaves of annona. Antidiabetic activity of aqueous leaf extract of annona. Different parts of annona squamosa l are used in folkloric medicine for the treatment of various diseases suresh et al. Annona squamosa are traditionally used for antidiabetic and antihyperlipidemic activity 12. Diuretic and antioxidant activities of the aqueous extract of. The present study investigated the possible therapeutic effects of annona squamosa a. Sithaphalaannona squamosa introduction it is a small tree possessing green coloured flowers.
The fruit of annona squamosa is different from annona muricata, which is wildly grown in india. Srikaya leaves can be used as antioxidants, antidiabetic, hepatoprotective, antitumor activities, and so forth. The fruits of this tree are consumed mainly in natura or as ingredients in juices and desserts. Annona squamosa custard apple is a native species of the west indies and was introduced to taiwan during the 17th century. The roots, leaves and seeds of annona squamosa contain several medicinal properties. Effect of ethanolic extract of different parts of plant. Physicochemical properties of the seed kernels and the oil. The antimalarial, antifungal, antibacterial, and larvicidal activity of extract from seed has been reported 16. Annonaceae also known as custard apple, is a new world fruit tree that has been naturalized throughout the tropics 5.
This plant is a rich source of pharmaceutically important anticancer compound acetogenins ages liaw et al. Original article antifungal and antioxidant activities of organic and aqueous extracts of annona squamosa linn. Hepatoprotective activity of hydroalcohilic extract of. The study aim was to assess the putative diuretic and antioxidant. Lots of work has been done on annona squamosa leaves but the. Hepatoprotective activity aqueous and alcoholic extract of leaves of annona squamosa were used for the screening of hepatoprotective activity. The effect produced by different extracts of fruit peel. The plant source is extensively used as detergenr, and as a curative of diseases. Antioxidant activity of seed extracts of annona squamosa. Pdf antioxidant activity of seed extracts of annona. This study was carried out to determine the antibacterial and antioxidant activities of organic seed extracts of annona squamosa. The crushed seeds have a diuretic action and are claimed to expel bladder and kidney stones, and effective in rheumatism 7. Research paper antioxidant activity of ethanolic extract.
The roots, leaves and seeds of annona squamosa contain several medicinal. Tomar and others published antidiabetic activity of annona squamosa l. The fruits were collected from local farms at mwea. The effectof aqueous and organic extracts from defatted seeds of plant was studied on a rat histiocytictumor cell line ak5. Shirwaikar a1, rajendran k, dinesh kumar c, bodla r. Antioxidant activity of seed extracts of annona squamosa and carica papaya. Annona squamosa l, belonging to the family annonaceae is a small ever green tree commonly found in india and originates from west indies and south america. The ethanol extract of annona squamosa was extracted by using soxhlet extraction apparatus. In the recent studies on annona squamosa all compounds showed moderate activity against a chloroquinesensitive strain and a chloroquineresistant strain of plasmodium falcifarum 25. Pdf insecticidal activity of ethanolic extract of leaves. Eshra et al physicochemical properties of the seed kernels and the oil of custard apple annona squamosa l. The extract of annona squamosa being a contact poison for insects can penetrate the body wall and tracheal system bringing about death probably lending the extract the insecticidal activity against sitophilus oryzae.
The average larval mortality percentage after 24 hours of exposure to the ethanolic leaf extract of a. Antifungal and antioxidant activities of organic and. Annona squamosa is a small, wellbranched tree or shrub from the family annonaceae that bears edible fruits called sugarapples or sweetsops. Different parts of annona squamosa such as fruits, seeds, leaves and barks have been used to treat many diseases. It tolerates a tropical lowland climate better than its relatives annona reticulata and annona cherimola whose fruits often share the same name helping make it the most widely cultivated of these species.
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